Novel Hexahydropyrimidine Compounds for Treating Malaria
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چکیده
منابع مشابه
Amodiaquine for treating malaria.
BACKGROUND Amodiaquine has been widely used to treat malaria. Due to reports of fatal adverse drug reactions, discontinuation or modification of its use has been suggested. OBJECTIVES The objective of this review was to assess the effects of amodiaquine for treating malaria. SEARCH STRATEGY We searched the Cochrane Infectious Diseases Group trials register and Medline. We also contacted res...
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BACKGROUND In Africa, malaria is often resistant to chloroquine and sulfadoxine-pyrimethamine. Chlorproguanil-dapsone is a potential alternative. OBJECTIVES To compare chlorproguanil-dapsone with other antimalarial drugs for treating uncomplicated falciparum malaria. SEARCH STRATEGY We searched the Cochrane Infectious Diseases Group Specialized Register (May 2004), CENTRAL (The Cochrane Lib...
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BACKGROUND Researchers are exploring the effects of adding treatments to the main antimalarial regimens in an attempt to reduce mortality from Plasmodium falciparum. Iron chelation is one potential chemotherapeutic adjuvant treatment. Before advocating adjunctive therapy, the effects of iron chelators in improving patient outcomes need to be examined. OBJECTIVES To assess the effects of iron-...
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ژورنال
عنوان ژورنال: ACS Medicinal Chemistry Letters
سال: 2021
ISSN: 1948-5875,1948-5875
DOI: 10.1021/acsmedchemlett.1c00171